![]() ![]() Many other labs around the world are also racing toward the same goal.īut Krisiloff and his colleagues say their company has gotten closer to making IVG a reality than anyone else by creating structures found in ovaries known as follicles, which are crucial for maturing eggs. "And for individuals, I think it's going to be life changing." Japanese scientists have already successfully completed IVG in mice and are trying to translate their success to humans. "How big of a deal it is for the world? I think it's going to be pretty big," says Seres, who has a background in in vitro fertilization. ![]() Transgender couples could also use IVG to have biologically related babies. IVG could also create sperm for lesbian couples, allowing them to have babies with genes from both women. A surrogate mother could then carry the resulting embryo through to the birth of a baby genetically related to both men. IVG could create eggs from one of Hurtado's cells that could then be fertilized with sperm from his partner. Laura Morton for NPR Conception Chief Scientific Officer Pablo Hurtado (from left), Chief Operating Officer Bianka Seres and CEO Matt Krisiloff are working on technology that could create human eggs from blood cells. I don't have that capacity right now." He adds, "I am devoting my life to trying to change that." ![]() "There is something intrinsic about sharing a life that is half me and half my husband. "Yeah, I'm gay, and it's something that got me so personally interested in this in the first place." "My personal biggest interest in it is it could allow same-sex couples to be able to have biological children together as well," Krisiloff says. So these lab-grown eggs would have that person's DNA. That's because induced pluripotent stem cells can be made from just a single cell from anyone's skin or blood. IVG would enable these women to have their own genetically related babies at any age. The experimental technology could help women who have lost their eggs to cancer treatment, women who have never been able to produce healthy eggs and women whose eggs are no longer viable because of their age. " really opens the door, if you can create eggs, to be able to help people have children that otherwise don't have options right now." "Basically, we're trying to turn a type of stem cell called an induced pluripotent stem cell into a human egg," Krisiloff says. "It's really exciting to be working on a technology that can change the lives of millions of humans."Ĭonception is trying to accelerate, and eventually commercialize, a field of biomedical research known as in vitro gametogenesis (IVG). "I personally think what we're doing will probably change many aspects of society as we know it," says Hurtado, the company's chief scientific officer. "So let me find them real quick," says Krisiloff as he turns to look for his co-founders, Pablo Hurtado and Bianka Seres, so they can explain Conception's mission. Nice to meet you," says one of the founders of Conception, a biotech startup that is trying to do something audacious: revolutionize the way humans reproduce. ![]() On a cloudy day on a gritty side street near the shore of San Francisco Bay, a young man answers the door at a low concrete building. ![]()
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